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Rev Esp Anestesiol Reanim ; 46(3): 106-10, 1999 Mar.
Artigo em Espanhol | MEDLINE | ID: mdl-10228375

RESUMO

OBJECTIVE: To evaluate the anesthetic efficacy of EMLA cream for alleviating pain associated with puncture and pressure in areas where venous catheters are normally inserted. MATERIAL AND METHODS: We performed a prospective, double blind study in 38 volunteers between 25 and 36 years of age, after obtaining informed consent. A 1.5 g dose of EMLA cream was applied to three sites on each patient: the back of the hand, the antecubital fossa and the side of the neck. Placebo cream with similar characteristics was applied to contralateral sites. Pain was evaluated on a visual analog scale (VAS, 0-10). Tactile sensitivity was assessed on a four-point scale (0 = no sensation; 1 = slight sensation; 2 = moderate, and 3 = strong). An analysis of variance study was performed to compare baseline scores to results over time, and placebo results to EMLA scores for each test site. RESULTS: The assessment of response to puncture and pressure gradually decreased over time for the sites where EMLA cream was applied, but not for the areas where placebo was applied. CONCLUSION: The efficacy of EMLA cream varies demonstrably depending on type of stimulus, site of application and time since application.


Assuntos
Anestésicos Combinados/administração & dosagem , Anestésicos Locais/administração & dosagem , Lidocaína/administração & dosagem , Prilocaína/administração & dosagem , Adulto , Método Duplo-Cego , Cotovelo , Emulsões , Eritema/etiologia , Eritema/prevenção & controle , Feminino , Mãos , Humanos , Combinação Lidocaína e Prilocaína , Masculino , Pescoço , Agulhas , Pomadas , Especificidade de Órgãos , Dor/etiologia , Dor/prevenção & controle , Propriocepção , Estudos Prospectivos , Prurido/etiologia , Prurido/prevenção & controle , Punções/efeitos adversos , Punções/instrumentação , Fatores de Tempo
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